Skin1 product guide
Choose Triple Lipid Restore 2:4:2 when your main priority is a lipid-rich moisturizer with ceramides and cholesterol. Choose A.G.E. Interrupter Advanced when you want the brand’s wrinkle-focused Proxylane cream. Both are rich moisturizers, but their ingredient blends and prices differ.
Triple Lipid costs $155 and centers on a stated 2% ceramides, 4% cholesterol and 2% fatty-acid blend. A.G.E. Interrupter Advanced costs $185 and adds Proxylane, niacinamide and fruit extracts in a creamy-balm texture. Both contain fragrant ingredients: Triple Lipid contains scented plant oils; A.G.E. lists fragrance/parfum.
USD prices checked October 24, 2026, before tax and shipping. Unit price = listed price ÷ package ounces. Weight ounces (oz) and fluid ounces (fl oz) measure different quantities.
| Product | US retailer | Size | Price | Price per ounce |
|---|---|---|---|---|
| SkinCeuticals Triple Lipid Restore 2:4:2 | Dermstore US | 1.6 fl oz | $155.00 | $96.88/fl oz |
| SkinCeuticals A.G.E. Interrupter Advanced | Dermstore US | 1.7 oz | $185.00 | $108.82/oz |
A moisturizer built around the stated 2% ceramides, 4% cholesterol and 2% fatty-acid ratio.
Consider: Includes lavender, rosemary and peppermint oils, plus linalool and limonene. A.G.E. Interrupter Advanced instead lists fragrance/parfum.
Use: Warm a small amount between fingertips, then apply gently to face, neck and chest twice daily. In the morning, apply after antioxidant serum and before sunscreen.
A rich cream with Proxylane, blueberry and pomegranate extracts, niacinamide and panthenol, positioned by SkinCeuticals for visible wrinkles.
Consider: No ceramide or cholesterol is named in this list. It contains fragrance, limonene, coumarin and linalool.
Use: Apply a thin, even layer to face, neck and chest twice daily. Use after antioxidant serum and before sunscreen in the morning; after retinol in the evening.
Choose the two options you are weighing. Read the ingredients below or compare how the products fit your routine here.
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Full published ingredient list
Aqua/Water/Eau, Dimethicone, Hydrogenated Polyisobutene, Glycerin, Cholesterol, C12-15 Alkyl Benzoate, Ceramide 3, Helianthus Annuus Seed Oil Unsaponifiables/Sunflower Seed Oil Unsaponifiables, Bis-PEG-18 Methyl Ether Dimethyl Silane, Sodium Polyacrylate, PEG-10 Dimethicone, Nylon-12, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Dimethicone/PEG-10/15 Crosspolymer, Phenoxyethanol, Disteardimonium Hectorite, Hydroxyethylpiperazine Ethane Sulfonic Acid, Ammonium Polyacryloyldimethyl Taurate, Chlorphenesin, Caprylyl Glycol, PEG/PPG-18/18 Dimethicone, Propylene Carbonate, Disodium EDTA, Acrylonitrile/Methyl Methacrylate/Vinylidene Chloride Copolymer, Adenosine, Dipropylene Glycol, Lavandula Angustifolia Oil/Lavender Oil, Rosmarinus Officinalis Leaf Oil/Rosemary Leaf Oil, T-Butyl Alcohol, Mentha Piperita Oil/Peppermint Oil, Sodium Citrate, Linalool, Isobutane, Ceramide EOP, BHT, Tocopherol, Limonene.
Full published ingredient list
Aqua / Water, Hydroxypropyl Tetrahydropyrantriol, Glycerin, Propylene Glycol, Stearic Acid, Butyrospermum Parkii Butter / Shea Butter, Hydroxyethylpiperazine Ethane Sulfonic Acid, Palmitic Acid, Pentylene Glycol, Oleyl Alcohol, Arachidyl Alcohol, Myristyl Myristate, Panthenol, Niacinamide, Dimethicone, Isononyl Isononanoate, Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone, Glyceryl Stearate, Candelilla Cera / Candelilla Wax, Behenyl Alcohol, PEG-100 Stearate, Sodium Polyacrylate, Pentaerythrityl Tetraisostearate, 4-T-Butylcyclohexanol, Arachidyl Glucoside, Caprylyl Glycol, Xanthan Gum, Chlorphenesin, Myristic Acid, Caprylic/Capric Triglyceride, Glycyrrhetinic Acid, Parfum / Fragrance, Sorbitol, Vaccinium Myrtillus Fruit Extract, Potassium Hydroxide, Adenosine, Citric Acid, Punica Granatum Fruit Extract, Limonene, Coumarin, Linalool, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate.
Dermstore US: A.G.E. Interrupter Advanced full ingredient list
Triple Lipid pairs cholesterol and ceramides with dimethicone, glycerin and emollients. It is the more direct fit if those barrier lipids are the reason you are buying a richer face cream.
A.G.E. Interrupter Advanced takes a different approach: hydroxypropyl tetrahydropyrantriol (Proxylane) appears near the start of its list, alongside glycerin, shea butter, niacinamide and panthenol. Its formula also contains blueberry and pomegranate extracts. SkinCeuticals positions this cream for visible lines and wrinkles.
SkinCeuticals describes Triple Lipid as silky and ultra-rich, and A.G.E. Advanced as a whipped, creamy balm. Both are substantial creams rather than light gel lotions.
If you avoid fragrance, neither is the obvious match. Triple Lipid names lavender, rosemary and peppermint oils; A.G.E. Advanced names parfum/fragrance. The full lists above make these differences easy to compare.
Both can be used morning and evening. Apply after serum and before sunscreen in the morning. For A.G.E. Advanced, the brand specifically places it after retinol at night.
Start by choosing the cream that meets your main need. Buying both adds $340 to the checkout; the formulas do not require one another to function as a moisturizer.
This comparison uses the current US A.G.E. Interrupter Advanced cream. The original A.G.E. Interrupter is its predecessor. A.G.E. Interrupter Ultra Serum is a separate serum, sold in a dropper bottle, rather than the cream compared here.
Both compared jars are listed by the brand as 48 mL, and A.G.E. Advanced costs $30 more per jar at the checked prices. A.G.E.’s jar also prints 1.7 oz / 48 g, so its unit cost is shown by weight; Triple Lipid’s retailer lists 1.6 fl oz, a volume measure. Compare the jar prices directly rather than treating those two ounce figures as the same unit.